The use, overuse, and abuse of antibiotics are accredited with creating antibiotic resistant strains due to natural selection. The concept of natural selection is an evolutionary process by which organisms adapt to their changing environment in order to survive, reproduce, and pass on their genes. In the case of antibiotics, certain bacteria become resistant when they are repeatedly exposed to them; this is because only those bacteria that possess certain genetic mutations can survive the drug’s effects. These resistant bacteria then continue to replicate and may even be passed along from person-to-person or between multiple species through transferable plasmids (small circles of DNA) carrying resistance genes. Over time these resistant bacteria become more common within a population and eventually dominate it completely. This phenomenon is known as “natural selection” because those genetically superior strains have been able to outcompete other weaker ones for resources – specifically survival in the presence of antibiotics.
In nature, antibiotic resistance often arises naturally when microorganisms live in close contact with one another in a biofilm—a densely populated community consisting mainly of bacteria embedded within an extracellular matrix composed mainly of polysaccharides such as slime or mucus—which allows for rapid horizontal gene transfer (HGT). HGT is the movement or exchange of genetic material between two different cell types without sexual reproduction taking place; it allows for rapidly evolving bacterial populations that can quickly acquire new abilities such as multi-drug resistance (MDR). Biofilms provide an ideal environment where MDR microbes can thrive due to the elevated expression levels of certain enzymes that degrade exogenous substances such as antibiotics; making them much harder if not impossible to kill with conventional treatments alone.
Antibiotic overuse and misuse however accelerates natural selection putting human health at risk by causing even more drug-resistant pathogens than what would otherwise exist naturally due primarily to widespread unrestricted use by humans including: physicians prescribing incorrect dosages/types for infections, veterinarians using too many drugs when treating animals, patients not completing courses correctly resulting in incomplete treatment cycles etc., all leading up now to serious implications beyond just personal health but also public health on a global scale since many forms of deadly infections have developed extremely high levels antimicrobial resistance (AMR). For instance Methicillin Resistant Staphylococcus Aureus (MRSA), extensively drug resistant tuberculosis (XDRTB), Acinetobacter baumannii & Pseudomonas aeruginosa have almost reached pandemic proportions throughout several countries worldwide; yet despite these alarming statistics there continues still today be little agreement amongst healthcare professionals regarding how best tackle this growing problem brought upon us by our own actions!
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