Postmortem toxicology.

Postmortem toxicology is the use of laboratory analysis to determine the presence, absence, and concentration of drugs or poisons in a person’s body at the time of death. It is performed on biological specimens such as blood, urine, or tissue samples taken from the decedent. The purpose of postmortem toxicology is to provide an objective assessment of a decedent’s drug and/or poison exposure prior to their death. Toxicological evidence can help answer questions during a legal investigation related to how and why someone died.

Postmortem toxicology.

The process begins with collection and preservation of relevant material that may contain drug and/or poison residues. Biological specimens are typically collected by medical examiners because they have access to deceased individuals. They also possess specialized training for proper sample collection techniques which are important for obtaining accurate results due to potential degradation after death. Commonly collected samples include blood from cardiac puncture or peripheral vessels, vitreous humor (the fluid inside the eye), bile, gastric contents (stomach contents), cerebrospinal fluid (fluid surrounding brain & spine), liver parenchyma (liver tissue) urine and hair follicles although other tissues may be obtained as well depending on circumstances surrounding the decedent’s death. Samples should be stored in air-tight containers at appropriate temperatures until testing can be performed or securely shipped for off-site analysis if needed.

Once specimens have been properly obtained they can then be analyzed in order to identify any drugs present in them at the time of death using methods such as liquid chromatography / mass spectrometry (LC/MS). LC/MS allows scientists to separate complex mixtures into individual components that can then be identified based on their chemical make-up so that even minute amounts can be detected accurately without interference from other substances present in samples if necessary. Detectable concentrations may also vary between different specimen types; for example levels detected in blood tend to reflect more recent exposures while those found in hair will represent cumulative exposures over longer periods since it takes much longer for drugs metabolized through certain pathways within our bodies before being excreted naturally Postmortem toxicology tests usually involve qualitative examinations where drugs present are identified but not necessarily quantified; however quantitative analyses utilizing specific toxins known concentrations standards may also be employed depending on what information needs determining posthumously regarding drug concentrations found relative living individuals taking similar substances under similar conditions .

Postmortem toxicology provides valuable insights into what happened leading up someone’s demise by providing verifiable evidence pertaining their suspected drug use prior passing away which could prove beneficial legal proceedings either exonerating parties involved wrongful crimes alleged against them acquitting justifiably prosecuting others guilty thereof . Additionally it helps formulate opinions concerning manner cause deaths when used conjunction with other investigative findings helping bring closure families friends loved ones lost too soon life .

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